Multi-omics analysis of two rat models reveals potential role of vesicle transport and autophagy in right ventricular remodeling
Abstract Right ventricular failure as a severe consequence of pulmonary arterial hypertension (PAH) is an independent risk factor for poor prognosis, although the pathogenesis of right ventricular remodeling (RVR) remains unclear.Exploring the shared molecular pathways and key molecules in the right ventricle in monocrotaline (MCT) and pulmonary ar